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    Gene name, or Protein Name, or Swiss -prot Accession
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Mouse Sonic hedgehog protein (aa 25-437)
Hhg1 Swiss Prot#
Q62226
Hhg1 Protein names
Sonic hedgehog protein (SHH) (HHG-1) [Cleaved into: Sonic hedgehog protein N-product; Sonic hedgehog protein C-product]
Hhg1 Gene names
Shh (Hhg1)
Organism
Mouse
Hhg1 Entry name
SHH_MOUSE
Hhg1 Codon optimized cDNA(gene) Clone
Hhg1 Cat #
RPX0176
Tag
Hhg1 contains A 6x histidine tag
Hhg1 Formulation
Liquid
Hhg1 Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Hhg1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Hhg1 Protein
t Hhg1 Cat #
PX0176
Hhg1 Source
t protein
t Hhg1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
t Hhg1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
t Hhg1 Activity
N/A
t Tag
t Hhg1 Contains A 6x histidine tag
t Hhg1 Formulation
Liquid
t Hhg1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Hhg1 family
Hedgehog family
Hhg1 Subcellular locations
Secreted > extracellular space. Cell membrane; Lipid-anchor.
Hhg1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).
Hhg1 Sequence
DDBJ EMBL GenBank
Hhg1 3D structure
ModBase
Hhg1 interaction
STRING
Hhg1 Proteomic
PRIDE
Hhg1 Genome annotation
Ensembl GeneID KEGG UCSC
Hhg1 Organism specific
CTD MGI
Hhg1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Hhg1 Gene expression
Bgee ArrayExpress Genevestigator
Hhg1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY