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Mouse Proto-oncogene protein Wnt-1 (aa 28-370)

Int-1 Swiss Prot#

P04426

Int-1 Protein names

Proto-oncogene protein Wnt-1

Int-1 Gene names

Wnt1 (Int-1) (Wnt-1)

Organism

Mouse

Int-1 Entry name

WNT1_MOUSE

Int-1 Codon optimized cDNA(gene) Clone

Int-1 Cat #

RPX0123

Tag

Int-1 contains A 6x histidine tag

Int-1 Formulation

Liquid

Int-1 Storage

Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Int-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Int-1 Protein

t Int-1 Cat #

PX0123

Int-1 Source

t protein

t Int-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

t Int-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

t Int-1 Activity

N/A

t Tag

t Int-1 Contains A 6x histidine tag

t Int-1 Formulation

Liquid

t Int-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Int-1 family

Wnt family

Int-1 Subcellular locations

Secreted > extracellular space > extracellular matrix.

Int-1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Proeminent role in the induction of the mesencephalon and cerebellum. May play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development.

Int-1 Sequence

DDBJ

EMBL

GenBank

Int-1 3D structure

ModBase

Int-1 interaction

STRING

Int-1 Proteomic

PRIDE

Int-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Int-1 Organism specific

CTD

MGI

Int-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Int-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Int-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY