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Mouse Neuronal migration protein doublecortin (aa 1-366)

Dcn Swiss Prot#

O88809

Dcn Protein names

Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin)

Dcn Gene names

Dcx (Dcn)

Organism

Mouse

Dcn Entry name

DCX_MOUSE

Dcn Codon optimized cDNA(gene) Clone

Dcn Cat #

RPX0122

Tag

Dcn contains A 6x histidine tag

Dcn Formulation

Liquid

Dcn Storage

Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dcn Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dcn Protein

t Dcn Cat #

PX0122

Dcn Source

t protein

t Dcn Applications

Western Blot, SDS-Page or may be used for other applications determined by user

t Dcn Purity

>90%, as determined by SDS-PAGE under reducing conditions

t Dcn Activity

N/A

t Tag

t Dcn Contains A 6x histidine tag

t Dcn Formulation

Liquid

t Dcn Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dcn family

-

Dcn Subcellular locations

Cytoplasm.

Dcn FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration (By similarity).

Dcn Sequence

DDBJ

EMBL

GenBank

Dcn 3D structure

ModBase

Dcn interaction

STRING

Dcn Proteomic

PRIDE

Dcn Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dcn Organism specific

CTD

MGI

Dcn Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dcn Gene expression

Bgee

ArrayExpress

Genevestigator

Dcn Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY