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Human Synaptotagmin-1 (aa 1-422)
SVP65 Swiss Prot#
P21579
SVP65 Protein names
Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)
SVP65 Gene names
SYT1 (SVP65) (SYT)
Organism
Human
SVP65 Entry name
SYT1_HUMAN
SVP65 Codon optimized cDNA(gene) Clone
SVP65 Cat #
RPX0033
Tag
SVP65 contains A 6x histidine tag
SVP65 Formulation
Liquid
SVP65 Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
SVP65 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant SVP65 Protein
t SVP65 Cat #
PX0033
SVP65 Source
t protein
t SVP65 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
t SVP65 Purity
>90%, as determined by SDS-PAGE under reducing conditions
t SVP65 Activity
N/A
t Tag
t SVP65 Contains A 6x histidine tag
t SVP65 Formulation
Liquid
t SVP65 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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SVP65 family
Synaptotagmin family
SVP65 Subcellular locations
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane; Single-pass membrane protein. Cytoplasm.
SVP65 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
SVP65 Sequence
DDBJ EMBL GenBank
SVP65 3D structure
ModBase
SVP65 interaction
STRING
SVP65 Proteomic
PRIDE
SVP65 Genome annotation
Ensembl GeneID KEGG UCSC
SVP65 Organism specific
CTD MGI
SVP65 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
SVP65 Gene expression
Bgee ArrayExpress Genevestigator
SVP65 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY