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| Human Synaptotagmin-1 (aa 1-422) |
| SVP65 Swiss Prot# | | P21579 |
| SVP65 Protein names | | Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65) |
| SVP65 Gene names | | SYT1 (SVP65) (SYT) |
| Organism | | Human |
| SVP65 Entry name | | SYT1_HUMAN |
| SVP65 Codon optimized cDNA(gene) Clone |
| SVP65 Cat # | | RPX0033 |
| Tag | | SVP65 contains A 6x histidine tag |
| SVP65 Formulation | | Liquid |
| SVP65 Storage | | Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| SVP65 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant SVP65 Protein |
| t SVP65 Cat # | | PX0033 |
| SVP65 Source | | t protein |
| t SVP65 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| t SVP65 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| t SVP65 Activity | | N/A |
| t Tag | | t SVP65 Contains A 6x histidine tag |
| t SVP65 Formulation | | Liquid |
| t SVP65 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant SVP65 Products | | For pricing and availability Click Here >>> |
| SVP65 family | | Synaptotagmin family |
| SVP65 Subcellular locations | | Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane; Single-pass membrane protein. Cytoplasm. |
| SVP65 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. |
| SVP65 Sequence | | DDBJ | EMBL | GenBank |
| SVP65 3D structure | | ModBase |
| SVP65 interaction | | STRING |
| SVP65 Proteomic | | PRIDE |
| SVP65 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| SVP65 Organism specific | | CTD | MGI |
| SVP65 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| SVP65 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| SVP65 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |