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Human Serine threonine-protein kinase PINK1 mitochondrial (aa 1-581)

PINK1 Swiss Prot#

Q9BXM7

PINK1 Protein names

Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK)

PINK1 Gene names

PINK1

Organism

Human

PINK1 Entry name

PINK1_HUMAN

PINK1 Codon optimized cDNA(gene) Clone

PINK1 Cat #

RPC0461

Tag

PINK1 contains A 6x histidine tag

PINK1 Formulation

Liquid

PINK1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PINK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PINK1 Protein

PINK1 Cat #

PC0461

PINK1 Source

recombinant

PINK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PINK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PINK1 Activity

N/A

Tag

PINK1 Contains A 6x histidine tag

PINK1 Formulation

Liquid

PINK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PINK1 family

Protein kinase superfamily, Ser/Thr protein kinase family

PINK1 Subcellular locations

Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm > cytosol.

PINK1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). It is necessary for PARK2 recruitement to dysfunctional mitochondria to initiate their degradation.

PINK1 Sequence

DDBJ

EMBL

GenBank

PINK1 3D structure

ModBase

PINK1 interaction

STRING

PINK1 Proteomic

PRIDE

PINK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

PINK1 Organism specific

CTD

MGI

PINK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PINK1 Gene expression

Bgee

ArrayExpress

Genevestigator

PINK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY