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Human Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (aa 1-562)

PIP5K1A Swiss Prot#

Q99755

PIP5K1A Protein names

Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (PtdIns(4)P-5-kinase alpha) (PIP5KIalpha) (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha)

PIP5K1A Gene names

PIP5K1A

Organism

Human

PIP5K1A Entry name

PI51A_HUMAN

PIP5K1A Codon optimized cDNA(gene) Clone

PIP5K1A Cat #

RPC0443

Tag

PIP5K1A contains A 6x histidine tag

PIP5K1A Formulation

Liquid

PIP5K1A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PIP5K1A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PIP5K1A Protein

PIP5K1A Cat #

PC0443

PIP5K1A Source

recombinant

PIP5K1A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PIP5K1A Purity

>90%, as determined by SDS-PAGE under reducing conditions

PIP5K1A Activity

N/A

Tag

PIP5K1A Contains A 6x histidine tag

PIP5K1A Formulation

Liquid

PIP5K1A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PIP5K1A family

-

PIP5K1A Subcellular locations

Cell membrane. Endomembrane system. Golgi apparatus > Golgi stack. Nucleus speckle.

PIP5K1A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Acts as an activator of TUT1 adenylyltransferase activity in nuclear speckles, thereby regulating mRNA polyadenylation of a select set of mRNAs. Contributes to the activation of PLD2.

PIP5K1A Sequence

DDBJ

EMBL

GenBank

PIP5K1A 3D structure

ModBase

PIP5K1A interaction

STRING

PIP5K1A Proteomic

PRIDE

PIP5K1A Genome annotation

Ensembl

GeneID

KEGG

UCSC

PIP5K1A Organism specific

CTD

MGI

PIP5K1A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PIP5K1A Gene expression

Bgee

ArrayExpress

Genevestigator

PIP5K1A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY