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Human 3-phosphoinositide-dependent protein kinase 1 (aa 1-556)
PDK1 Swiss Prot#
O15530
PDK1 Protein names
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
PDK1 Gene names
PDPK1 (PDK1)
Organism
Human
PDK1 Entry name
PDPK1_HUMAN
PDK1 Codon optimized cDNA(gene) Clone
PDK1 Cat #
RPC0439
Tag
PDK1 contains A 6x histidine tag
PDK1 Formulation
Liquid
PDK1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
PDK1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant PDK1 Protein
PDK1 Cat #
PC0439
PDK1 Source
recombinant
PDK1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
PDK1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
PDK1 Activity
N/A
Tag
PDK1 Contains A 6x histidine tag
PDK1 Formulation
Liquid
PDK1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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PDK1 family
Protein kinase superfamily, AGC Ser/Thr protein kinase family, PDK1 subfamily
PDK1 Subcellular locations
Cytoplasm. Membrane; Peripheral membrane protein.
PDK1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.
PDK1 Sequence
DDBJ EMBL GenBank
PDK1 3D structure
ModBase
PDK1 interaction
STRING
PDK1 Proteomic
PRIDE
PDK1 Genome annotation
Ensembl GeneID KEGG UCSC
PDK1 Organism specific
CTD MGI
PDK1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PDK1 Gene expression
Bgee ArrayExpress Genevestigator
PDK1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY