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Human 5'-AMP-activated protein kinase catalytic subunit alpha-1 (aa 1-552)

AMPK1 Swiss Prot#

Q13131

AMPK1 Protein names

5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK alpha-1 chain) (EC 2.7.11.1)

AMPK1 Gene names

PRKAA1 (AMPK1)

Organism

Human

AMPK1 Entry name

AAPK1_HUMAN

AMPK1 Codon optimized cDNA(gene) Clone

AMPK1 Cat #

RPC0429

Tag

AMPK1 contains A 6x histidine tag

AMPK1 Formulation

Liquid

AMPK1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

AMPK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant AMPK1 Protein

AMPK1 Cat #

PC0429

AMPK1 Source

recombinant

AMPK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

AMPK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

AMPK1 Activity

N/A

Tag

AMPK1 Contains A 6x histidine tag

AMPK1 Formulation

Liquid

AMPK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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AMPK1 family

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily

AMPK1 Subcellular locations

-

AMPK1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

AMPK1 Sequence

DDBJ

EMBL

GenBank

AMPK1 3D structure

ModBase

AMPK1 interaction

STRING

AMPK1 Proteomic

PRIDE

AMPK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

AMPK1 Organism specific

CTD

MGI

AMPK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

AMPK1 Gene expression

Bgee

ArrayExpress

Genevestigator

AMPK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY