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Human Receptor-interacting serine threonine-protein kinase 2 (aa 1-540)

CARDIAK Swiss Prot#

O43353

CARDIAK Protein names

Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase)

CARDIAK Gene names

RIPK2 (CARDIAK) (RICK) (RIP2) (UNQ277/PRO314/PRO34092)

Organism

Human

CARDIAK Entry name

RIPK2_HUMAN

CARDIAK Codon optimized cDNA(gene) Clone

CARDIAK Cat #

RPC0418

Tag

CARDIAK contains A 6x histidine tag

CARDIAK Formulation

Liquid

CARDIAK Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CARDIAK Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CARDIAK Protein

CARDIAK Cat #

PC0418

CARDIAK Source

recombinant

CARDIAK Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CARDIAK Purity

>90%, as determined by SDS-PAGE under reducing conditions

CARDIAK Activity

N/A

Tag

CARDIAK Contains A 6x histidine tag

CARDIAK Formulation

Liquid

CARDIAK Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CARDIAK family

Protein kinase superfamily, TKL Ser/Thr protein kinase family

CARDIAK Subcellular locations

Cytoplasm.

CARDIAK FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B.

CARDIAK Sequence

DDBJ

EMBL

GenBank

CARDIAK 3D structure

ModBase

CARDIAK interaction

STRING

CARDIAK Proteomic

PRIDE

CARDIAK Genome annotation

Ensembl

GeneID

KEGG

UCSC

CARDIAK Organism specific

CTD

MGI

CARDIAK Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CARDIAK Gene expression

Bgee

ArrayExpress

Genevestigator

CARDIAK Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY