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Human Ceramide kinase (aa 1-537)

CERK Swiss Prot#

Q8TCT0

CERK Protein names

Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)

CERK Gene names

CERK (KIAA1646)

Organism

Human

CERK Entry name

CERK1_HUMAN

CERK Codon optimized cDNA(gene) Clone

CERK Cat #

RPC0412

Tag

CERK contains A 6x histidine tag

CERK Formulation

Liquid

CERK Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CERK Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CERK Protein

CERK Cat #

PC0412

CERK Source

recombinant

CERK Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CERK Purity

>90%, as determined by SDS-PAGE under reducing conditions

CERK Activity

N/A

Tag

CERK Contains A 6x histidine tag

CERK Formulation

Liquid

CERK Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CERK family

-

CERK Subcellular locations

Cytoplasm. Membrane; Peripheral membrane protein.

CERK FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

CERK Sequence

DDBJ

EMBL

GenBank

CERK 3D structure

ModBase

CERK interaction

STRING

CERK Proteomic

PRIDE

CERK Genome annotation

Ensembl

GeneID

KEGG

UCSC

CERK Organism specific

CTD

MGI

CERK Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CERK Gene expression

Bgee

ArrayExpress

Genevestigator

CERK Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY