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Human Calcium calmodulin-dependent kinase type II alpha (aa 1-478)

CAMKA Swiss Prot#

Q9UQM7

CAMKA Protein names

Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)

CAMKA Gene names

CAMK2A (CAMKA) (KIAA0968)

Organism

Human

CAMKA Entry name

KCC2A_HUMAN

CAMKA Codon optimized cDNA(gene) Clone

CAMKA Cat #

RPC0341

Tag

CAMKA contains A 6x histidine tag

CAMKA Formulation

Liquid

CAMKA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CAMKA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CAMKA Protein

CAMKA Cat #

PC0341

CAMKA Source

recombinant

CAMKA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CAMKA Purity

>90%, as determined by SDS-PAGE under reducing conditions

CAMKA Activity

N/A

Tag

CAMKA Contains A 6x histidine tag

CAMKA Formulation

Liquid

CAMKA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CAMKA family

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily

CAMKA Subcellular locations

Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse.

CAMKA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).

CAMKA Sequence

DDBJ

EMBL

GenBank

CAMKA 3D structure

ModBase

CAMKA interaction

STRING

CAMKA Proteomic

PRIDE

CAMKA Genome annotation

Ensembl

GeneID

KEGG

UCSC

CAMKA Organism specific

CTD

MGI

CAMKA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CAMKA Gene expression

Bgee

ArrayExpress

Genevestigator

CAMKA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY