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Human Mitogen-activated protein kinase 9 (aa 1-424)
JNK2 Swiss Prot#
P45984
JNK2 Protein names
Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55)
JNK2 Gene names
MAPK9 (JNK2) (PRKM9)
Organism
Human
JNK2 Entry name
MK09_HUMAN
JNK2 Codon optimized cDNA(gene) Clone
JNK2 Cat #
RPC0285
Tag
JNK2 contains A 6x histidine tag
JNK2 Formulation
Liquid
JNK2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
JNK2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant JNK2 Protein
JNK2 Cat #
PC0285
JNK2 Source
recombinant
JNK2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
JNK2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
JNK2 Activity
N/A
Tag
JNK2 Contains A 6x histidine tag
JNK2 Formulation
Liquid
JNK2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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JNK2 family
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
JNK2 Subcellular locations
-
JNK2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.; FUNCTION: JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
JNK2 Sequence
DDBJ EMBL GenBank
JNK2 3D structure
ModBase
JNK2 interaction
STRING
JNK2 Proteomic
PRIDE
JNK2 Genome annotation
Ensembl GeneID KEGG UCSC
JNK2 Organism specific
CTD MGI
JNK2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
JNK2 Gene expression
Bgee ArrayExpress Genevestigator
JNK2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY