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| Human Mitogen-activated protein kinase 9 (aa 1-424) |
| JNK2 Swiss Prot# | | P45984 |
| JNK2 Protein names | | Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55) |
| JNK2 Gene names | | MAPK9 (JNK2) (PRKM9) |
| Organism | | Human |
| JNK2 Entry name | | MK09_HUMAN |
| JNK2 Codon optimized cDNA(gene) Clone |
| JNK2 Cat # | | RPC0285 |
| Tag | | JNK2 contains A 6x histidine tag |
| JNK2 Formulation | | Liquid |
| JNK2 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| JNK2 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant JNK2 Protein |
| JNK2 Cat # | | PC0285 |
| JNK2 Source | | recombinant |
| JNK2 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| JNK2 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| JNK2 Activity | | N/A |
| Tag | | JNK2 Contains A 6x histidine tag |
| JNK2 Formulation | | Liquid |
| JNK2 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant JNK2 Products | | For pricing and availability Click Here >>> |
| JNK2 family | | Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily |
| JNK2 Subcellular locations | | - |
| JNK2 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.; FUNCTION: JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it. |
| JNK2 Sequence | | DDBJ | EMBL | GenBank |
| JNK2 3D structure | | ModBase |
| JNK2 interaction | | STRING |
| JNK2 Proteomic | | PRIDE |
| JNK2 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| JNK2 Organism specific | | CTD | MGI |
| JNK2 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| JNK2 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| JNK2 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |