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Human Acylglycerol kinase mitochondrial (aa 1-422)
MULK Swiss Prot#
Q53H12
MULK Protein names
Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.94) (EC 2.7.1.107) (Multiple substrate lipid kinase) (Multi-substrate lipid kinase) (MuLK) (HsMuLK)
MULK Gene names
AGK (MULK)
Organism
Human
MULK Entry name
AGK_HUMAN
MULK Codon optimized cDNA(gene) Clone
MULK Cat #
RPC0282
Tag
MULK contains A 6x histidine tag
MULK Formulation
Liquid
MULK Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
MULK Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant MULK Protein
MULK Cat #
PC0282
MULK Source
recombinant
MULK Applications
Western Blot, SDS-Page or may be used for other applications determined by user
MULK Purity
>90%, as determined by SDS-PAGE under reducing conditions
MULK Activity
N/A
Tag
MULK Contains A 6x histidine tag
MULK Formulation
Liquid
MULK Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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MULK family
-
MULK Subcellular locations
Mitochondrion membrane.
MULK FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
MULK Sequence
DDBJ EMBL GenBank
MULK 3D structure
ModBase
MULK interaction
STRING
MULK Proteomic
PRIDE
MULK Genome annotation
Ensembl GeneID KEGG UCSC
MULK Organism specific
CTD MGI
MULK Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MULK Gene expression
Bgee ArrayExpress Genevestigator
MULK Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY