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Human Docking protein 2 (aa 1-412)

DOK2 Swiss Prot#

O60496

DOK2 Protein names

Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2))

DOK2 Gene names

DOK2

Organism

Human

DOK2 Entry name

DOK2_HUMAN

DOK2 Codon optimized cDNA(gene) Clone

DOK2 Cat #

RPC0260

Tag

DOK2 contains A 6x histidine tag

DOK2 Formulation

Liquid

DOK2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DOK2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DOK2 Protein

DOK2 Cat #

PC0260

DOK2 Source

recombinant

DOK2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DOK2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DOK2 Activity

N/A

Tag

DOK2 Contains A 6x histidine tag

DOK2 Formulation

Liquid

DOK2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DOK2 family

DOK family, Type A subfamily

DOK2 Subcellular locations

-

DOK2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity).

DOK2 Sequence

DDBJ

EMBL

GenBank

DOK2 3D structure

ModBase

DOK2 interaction

STRING

DOK2 Proteomic

PRIDE

DOK2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DOK2 Organism specific

CTD

MGI

DOK2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DOK2 Gene expression

Bgee

ArrayExpress

Genevestigator

DOK2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY