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Human (3-methyl-2-oxobutanoate dehydrogenase (aa 1-412)

BCKDK Swiss Prot#

O14874

BCKDK Protein names

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN)

BCKDK Gene names

BCKDK

Organism

Human

BCKDK Entry name

BCKD_HUMAN

BCKDK Codon optimized cDNA(gene) Clone

BCKDK Cat #

RPC0259

Tag

BCKDK contains A 6x histidine tag

BCKDK Formulation

Liquid

BCKDK Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BCKDK Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BCKDK Protein

BCKDK Cat #

PC0259

BCKDK Source

recombinant

BCKDK Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BCKDK Purity

>90%, as determined by SDS-PAGE under reducing conditions

BCKDK Activity

N/A

Tag

BCKDK Contains A 6x histidine tag

BCKDK Formulation

Liquid

BCKDK Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BCKDK family

PDK/BCKDK protein kinase family

BCKDK Subcellular locations

Mitochondrion matrix.

BCKDK FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex (By similarity).

BCKDK Sequence

DDBJ

EMBL

GenBank

BCKDK 3D structure

ModBase

BCKDK interaction

STRING

BCKDK Proteomic

PRIDE

BCKDK Genome annotation

Ensembl

GeneID

KEGG

UCSC

BCKDK Organism specific

CTD

MGI

BCKDK Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BCKDK Gene expression

Bgee

ArrayExpress

Genevestigator

BCKDK Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY