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Human MAP kinase-activated protein kinase 2 (aa 1-400)

MAPKAPK2 Swiss Prot#

P49137

MAPKAPK2 Protein names

MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) (EC 2.7.11.1)

MAPKAPK2 Gene names

MAPKAPK2

Organism

Human

MAPKAPK2 Entry name

MAPK2_HUMAN

MAPKAPK2 Codon optimized cDNA(gene) Clone

MAPKAPK2 Cat #

RPC0243

Tag

MAPKAPK2 contains A 6x histidine tag

MAPKAPK2 Formulation

Liquid

MAPKAPK2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MAPKAPK2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MAPKAPK2 Protein

MAPKAPK2 Cat #

PC0243

MAPKAPK2 Source

recombinant

MAPKAPK2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MAPKAPK2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MAPKAPK2 Activity

N/A

Tag

MAPKAPK2 Contains A 6x histidine tag

MAPKAPK2 Formulation

Liquid

MAPKAPK2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MAPKAPK2 family

Protein kinase superfamily, CAMK Ser/Thr protein kinase family

MAPKAPK2 Subcellular locations

-

MAPKAPK2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.

MAPKAPK2 Sequence

DDBJ

EMBL

GenBank

MAPKAPK2 3D structure

ModBase

MAPKAPK2 interaction

STRING

MAPKAPK2 Proteomic

PRIDE

MAPKAPK2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MAPKAPK2 Organism specific

CTD

MGI

MAPKAPK2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MAPKAPK2 Gene expression

Bgee

ArrayExpress

Genevestigator

MAPKAPK2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY