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Human Dual specificity mitogen-activated protein kinase 4 (aa 1-399)

JNKK1 Swiss Prot#

P45985

JNKK1 Protein names

Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (EC 2.7.12.2) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1)

JNKK1 Gene names

MAP2K4 (JNKK1) (MKK4) (PRKMK4) (SERK1)

Organism

Human

JNKK1 Entry name

MP2K4_HUMAN

JNKK1 Codon optimized cDNA(gene) Clone

JNKK1 Cat #

RPC0241

Tag

JNKK1 contains A 6x histidine tag

JNKK1 Formulation

Liquid

JNKK1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

JNKK1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant JNKK1 Protein

JNKK1 Cat #

PC0241

JNKK1 Source

recombinant

JNKK1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

JNKK1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

JNKK1 Activity

N/A

Tag

JNKK1 Contains A 6x histidine tag

JNKK1 Formulation

Liquid

JNKK1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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JNKK1 family

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily

JNKK1 Subcellular locations

-

JNKK1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

JNKK1 Sequence

DDBJ

EMBL

GenBank

JNKK1 3D structure

ModBase

JNKK1 interaction

STRING

JNKK1 Proteomic

PRIDE

JNKK1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

JNKK1 Organism specific

CTD

MGI

JNKK1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

JNKK1 Gene expression

Bgee

ArrayExpress

Genevestigator

JNKK1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY