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Human Serine threonine-protein kinase VRK1 (aa 1-396)
VRK1 Swiss Prot#
Q99986
VRK1 Protein names
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
VRK1 Gene names
VRK1
Organism
Human
VRK1 Entry name
VRK1_HUMAN
VRK1 Codon optimized cDNA(gene) Clone
VRK1 Cat #
RPC0238
Tag
VRK1 contains A 6x histidine tag
VRK1 Formulation
Liquid
VRK1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
VRK1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant VRK1 Protein
VRK1 Cat #
PC0238
VRK1 Source
recombinant
VRK1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
VRK1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
VRK1 Activity
N/A
Tag
VRK1 Contains A 6x histidine tag
VRK1 Formulation
Liquid
VRK1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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VRK1 family
Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily
VRK1 Subcellular locations
Nucleus.
VRK1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Serine/threonine kinase that phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2.
VRK1 Sequence
DDBJ EMBL GenBank
VRK1 3D structure
ModBase
VRK1 interaction
STRING
VRK1 Proteomic
PRIDE
VRK1 Genome annotation
Ensembl GeneID KEGG UCSC
VRK1 Organism specific
CTD MGI
VRK1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
VRK1 Gene expression
Bgee ArrayExpress Genevestigator
VRK1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY