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Human Na(+) H(+) exchange regulatory cofactor NHE-RF2 (aa 1-337)

NHERF2 Swiss Prot#

Q15599

NHERF2 Protein names

Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2)

NHERF2 Gene names

SLC9A3R2 (NHERF2)

Organism

Human

NHERF2 Entry name

NHRF2_HUMAN

NHERF2 Codon optimized cDNA(gene) Clone

NHERF2 Cat #

RPC0154

Tag

NHERF2 contains A 6x histidine tag

NHERF2 Formulation

Liquid

NHERF2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NHERF2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NHERF2 Protein

NHERF2 Cat #

PC0154

NHERF2 Source

recombinant

NHERF2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NHERF2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NHERF2 Activity

N/A

Tag

NHERF2 Contains A 6x histidine tag

NHERF2 Formulation

Liquid

NHERF2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NHERF2 family

-

NHERF2 Subcellular locations

Endomembrane system; Peripheral membrane protein. Nucleus. Apical cell membrane.

NHERF2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.

NHERF2 Sequence

DDBJ

EMBL

GenBank

NHERF2 3D structure

ModBase

NHERF2 interaction

STRING

NHERF2 Proteomic

PRIDE

NHERF2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NHERF2 Organism specific

CTD

MGI

NHERF2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NHERF2 Gene expression

Bgee

ArrayExpress

Genevestigator

NHERF2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY