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Human Mitogen-activated protein kinase organizer 1 (aa 1-315)

MORG1 Swiss Prot#

Q9BRX9

MORG1 Protein names

Mitogen-activated protein kinase organizer 1 (MAPK organizer 1)

MORG1 Gene names

MORG1

Organism

Human

MORG1 Entry name

WDR83_HUMAN

MORG1 Codon optimized cDNA(gene) Clone

MORG1 Cat #

RPC0130

Tag

MORG1 contains A 6x histidine tag

MORG1 Formulation

Liquid

MORG1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MORG1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MORG1 Protein

MORG1 Cat #

PC0130

MORG1 Source

recombinant

MORG1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MORG1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MORG1 Activity

N/A

Tag

MORG1 Contains A 6x histidine tag

MORG1 Formulation

Liquid

MORG1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MORG1 family

WD repeat MORG1 family

MORG1 Subcellular locations

Cytoplasm. Nucleus.

MORG1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

MORG1 Sequence

DDBJ

EMBL

GenBank

MORG1 3D structure

ModBase

MORG1 interaction

STRING

MORG1 Proteomic

PRIDE

MORG1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MORG1 Organism specific

CTD

MGI

MORG1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MORG1 Gene expression

Bgee

ArrayExpress

Genevestigator

MORG1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY