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Human E3 ubiquitin-protein ligase RNF138 (aa 1-245)

NARF Swiss Prot#

Q8WVD3

NARF Protein names

E3 ubiquitin-protein ligase RNF138 (EC 6.3.2.-) (RING finger protein 138) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF)

NARF Gene names

RNF138 (NARF) (HSD4) (HSD-4)

Organism

Human

NARF Entry name

RN138_HUMAN

NARF Codon optimized cDNA(gene) Clone

NARF Cat #

RPC0076

Tag

NARF contains A 6x histidine tag

NARF Formulation

Liquid

NARF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NARF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NARF Protein

NARF Cat #

PC0076

NARF Source

recombinant

NARF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NARF Purity

>90%, as determined by SDS-PAGE under reducing conditions

NARF Activity

N/A

Tag

NARF Contains A 6x histidine tag

NARF Formulation

Liquid

NARF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NARF family

-

NARF Subcellular locations

-

NARF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.

NARF Sequence

DDBJ

EMBL

GenBank

NARF 3D structure

ModBase

NARF interaction

STRING

NARF Proteomic

PRIDE

NARF Genome annotation

Ensembl

GeneID

KEGG

UCSC

NARF Organism specific

CTD

MGI

NARF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NARF Gene expression

Bgee

ArrayExpress

Genevestigator

NARF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY