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Human Cyclin-dependent kinase inhibitor 2A (aa 1-156)
CDKN2 Swiss Prot#
P42771
CDKN2 Protein names
Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16INK4A) (p16-INK4) (Multiple tumor suppressor 1) (MTS-1)
CDKN2 Gene names
CDKN2A (CDKN2) (MTS1)
Organism
Human
CDKN2 Entry name
CD2A1_HUMAN
CDKN2 Codon optimized cDNA(gene) Clone
CDKN2 Cat #
RPC0018
Tag
CDKN2 contains A 6x histidine tag
CDKN2 Formulation
Liquid
CDKN2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
CDKN2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant CDKN2 Protein
CDKN2 Cat #
PC0018
CDKN2 Source
recombinant
CDKN2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
CDKN2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
CDKN2 Activity
N/A
Tag
CDKN2 Contains A 6x histidine tag
CDKN2 Formulation
Liquid
CDKN2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CDKN2 family
CDKN2 cyclin-dependent kinase inhibitor family
CDKN2 Subcellular locations
Cytoplasm. Nucleus.
CDKN2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
CDKN2 Sequence
DDBJ EMBL GenBank
CDKN2 3D structure
ModBase
CDKN2 interaction
STRING
CDKN2 Proteomic
PRIDE
CDKN2 Genome annotation
Ensembl GeneID KEGG UCSC
CDKN2 Organism specific
CTD MGI
CDKN2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CDKN2 Gene expression
Bgee ArrayExpress Genevestigator
CDKN2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY