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Human mRNA-capping enzyme (aa 1-597)

CAP1A Swiss Prot#

O60942

CAP1A Protein names

mRNA-capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'-triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase) mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]

CAP1A Gene names

RNGTT (CAP1A)

Organism

Human

CAP1A Entry name

MCE1_HUMAN

CAP1A Codon optimized cDNA(gene) Clone

CAP1A Cat #

RPT0376

Tag

CAP1A contains A 6x histidine tag

CAP1A Formulation

Liquid

CAP1A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CAP1A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CAP1A Protein

CAP1A Cat #

PT0376

CAP1A Source

recombinant

CAP1A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CAP1A Purity

>90%, as determined by SDS-PAGE under reducing conditions

CAP1A Activity

N/A

Tag

CAP1A Contains A 6x histidine tag

CAP1A Formulation

Liquid

CAP1A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CAP1A family

Non-receptor class of the protein-tyrosine phosphatase family; Eukaryotic GTase family

CAP1A Subcellular locations

Nucleus.

CAP1A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.

CAP1A Sequence

DDBJ

EMBL

GenBank

CAP1A 3D structure

ModBase

CAP1A interaction

STRING

CAP1A Proteomic

PRIDE

CAP1A Proteomic

Ensembl

GeneID

KEGG

UCSC

CAP1A Organism specific

CTD

MGI

CAP1A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CAP1A Gene expression

Bgee

ArrayExpress

Genevestigator

CAP1A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY