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| Human Tyrosine-protein phosphatase non-receptor type 6 (aa 1-595) |
| HCP Swiss Prot# | | P29350 |
| HCP Protein names | | Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1) |
| HCP Gene names | | PTPN6 (HCP) (PTP1C) |
| Organism | | Human |
| HCP Entry name | | PTN6_HUMAN |
| HCP Codon optimized cDNA(gene) Clone |
| HCP Cat # | | RPT0375 |
| Tag | | HCP contains A 6x histidine tag |
| HCP Formulation | | Liquid |
| HCP Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| HCP Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant HCP Protein |
| HCP Cat # | | PT0375 |
| HCP Source | | recombinant |
| HCP Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| HCP Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| HCP Activity | | N/A |
| Tag | | HCP Contains A 6x histidine tag |
| HCP Formulation | | Liquid |
| HCP Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant HCP Products | | For pricing and availability Click Here >>> |
| HCP family | | Protein-tyrosine phosphatase family, Non-receptor class 2 subfamily |
| HCP Subcellular locations | | Cytoplasm. Nucleus. |
| HCP FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. |
| HCP Sequence | | DDBJ | EMBL | GenBank |
| HCP 3D structure | | ModBase |
| HCP interaction | | STRING |
| HCP Proteomic | | PRIDE |
| HCP Proteomic | | Ensembl | GeneID | KEGG | UCSC |
| HCP Organism specific | | CTD | MGI |
| HCP Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| HCP Gene expression | | Bgee | ArrayExpress | Genevestigator |
| HCP Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |