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Human Dual specificity protein phosphatase CDC14A (aa 1-594)

CDC14A Swiss Prot#

Q9UNH5

CDC14A Protein names

Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A)

CDC14A Gene names

CDC14A

Organism

Human

CDC14A Entry name

CC14A_HUMAN

CDC14A Codon optimized cDNA(gene) Clone

CDC14A Cat #

RPT0374

Tag

CDC14A contains A 6x histidine tag

CDC14A Formulation

Liquid

CDC14A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CDC14A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CDC14A Protein

CDC14A Cat #

PT0374

CDC14A Source

recombinant

CDC14A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CDC14A Purity

>90%, as determined by SDS-PAGE under reducing conditions

CDC14A Activity

N/A

Tag

CDC14A Contains A 6x histidine tag

CDC14A Formulation

Liquid

CDC14A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CDC14A family

Protein-tyrosine phosphatase family, Non-receptor class CDC14 subfamily

CDC14A Subcellular locations

Nucleus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle.

CDC14A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.

CDC14A Sequence

DDBJ

EMBL

GenBank

CDC14A 3D structure

ModBase

CDC14A interaction

STRING

CDC14A Proteomic

PRIDE

CDC14A Proteomic

Ensembl

GeneID

KEGG

UCSC

CDC14A Organism specific

CTD

MGI

CDC14A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CDC14A Gene expression

Bgee

ArrayExpress

Genevestigator

CDC14A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY