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Human Serine threonine-protein kinase PAK 4 (aa 1- 591)

KIAA1142 Swiss Prot#

O96013

KIAA1142 Protein names

Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)

KIAA1142 Gene names

PAK4 (KIAA1142)

Organism

Human

KIAA1142 Entry name

PAK4_HUMAN

KIAA1142 Codon optimized cDNA(gene) Clone

KIAA1142 Cat #

RPT0370

Tag

KIAA1142 contains A 6x histidine tag

KIAA1142 Formulation

Liquid

KIAA1142 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

KIAA1142 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant KIAA1142 Protein

KIAA1142 Cat #

PT0370

KIAA1142 Source

recombinant

KIAA1142 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

KIAA1142 Purity

>90%, as determined by SDS-PAGE under reducing conditions

KIAA1142 Activity

N/A

Tag

KIAA1142 Contains A 6x histidine tag

KIAA1142 Formulation

Liquid

KIAA1142 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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KIAA1142 family

Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily

KIAA1142 Subcellular locations

-

KIAA1142 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2.

KIAA1142 Sequence

DDBJ

EMBL

GenBank

KIAA1142 3D structure

ModBase

KIAA1142 interaction

STRING

KIAA1142 Proteomic

PRIDE

KIAA1142 Proteomic

Ensembl

GeneID

KEGG

UCSC

KIAA1142 Organism specific

CTD

MGI

KIAA1142 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KIAA1142 Gene expression

Bgee

ArrayExpress

Genevestigator

KIAA1142 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY