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Human Serine threonine-protein phosphatase 2A (aa 1-524)

KIAA0044 Swiss Prot#

Q13362

KIAA0044 Protein names

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (Renal carcinoma antigen NY-REN-29)

KIAA0044 Gene names

PPP2R5C (KIAA0044)

Organism

Human

KIAA0044 Entry name

2A5G_HUMAN

KIAA0044 Codon optimized cDNA(gene) Clone

KIAA0044 Cat #

RPT0341

Tag

KIAA0044 contains A 6x histidine tag

KIAA0044 Formulation

Liquid

KIAA0044 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

KIAA0044 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant KIAA0044 Protein

KIAA0044 Cat #

PT0341

KIAA0044 Source

recombinant

KIAA0044 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

KIAA0044 Purity

>90%, as determined by SDS-PAGE under reducing conditions

KIAA0044 Activity

N/A

Tag

KIAA0044 Contains A 6x histidine tag

KIAA0044 Formulation

Liquid

KIAA0044 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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KIAA0044 family

Phosphatase 2A regulatory subunit B56 family

KIAA0044 Subcellular locations

Nucleus. Chromosome > centromere.

KIAA0044 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.

KIAA0044 Sequence

DDBJ

EMBL

GenBank

KIAA0044 3D structure

ModBase

KIAA0044 interaction

STRING

KIAA0044 Proteomic

PRIDE

KIAA0044 Proteomic

Ensembl

GeneID

KEGG

UCSC

KIAA0044 Organism specific

CTD

MGI

KIAA0044 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KIAA0044 Gene expression

Bgee

ArrayExpress

Genevestigator

KIAA0044 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY