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Human Erythropoietin receptor (aa 1-

EPOR Swiss Prot#

P19235

EPOR Protein names

Erythropoietin receptor (EPO-R)

EPOR Gene names

EPOR

Organism

Human

EPOR Entry name

EPOR_HUMAN

EPOR Codon optimized cDNA(gene) Clone

EPOR Cat #

RPT0328

Tag

EPOR contains A 6x histidine tag

EPOR Formulation

Liquid

EPOR Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EPOR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EPOR Protein

EPOR Cat #

PT0328

EPOR Source

recombinant

EPOR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EPOR Purity

>90%, as determined by SDS-PAGE under reducing conditions

EPOR Activity

N/A

Tag

EPOR Contains A 6x histidine tag

EPOR Formulation

Liquid

EPOR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EPOR family

Type I cytokine receptor family, Type 1 subfamily

EPOR Subcellular locations

Cell membrane; Single-pass type I membrane protein. Secreted.

EPOR FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.; FUNCTION: Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

EPOR Sequence

DDBJ

EMBL

GenBank

EPOR 3D structure

ModBase

EPOR interaction

STRING

EPOR Proteomic

PRIDE

EPOR Proteomic

Ensembl

GeneID

KEGG

UCSC

EPOR Organism specific

CTD

MGI

EPOR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EPOR Gene expression

Bgee

ArrayExpress

Genevestigator

EPOR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY