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Human Serine threonine-protein phosphatase 2A (aa 1-453)
KIAA1541 Swiss Prot#
Q66LE6
KIAA1541 Protein names
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A, subunit B, B-delta isoform) (PP2A, subunit B, B55-delta isoform) (PP2A, subunit B, PR55-delta isoform) (PP2A, subunit B, R2-delta isoform)
KIAA1541 Gene names
PPP2R2D (KIAA1541)
Organism
Human
KIAA1541 Entry name
2ABD_HUMAN
KIAA1541 Codon optimized cDNA(gene) Clone
KIAA1541 Cat #
RPT0285
Tag
KIAA1541 contains A 6x histidine tag
KIAA1541 Formulation
Liquid
KIAA1541 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
KIAA1541 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant KIAA1541 Protein
KIAA1541 Cat #
PT0285
KIAA1541 Source
recombinant
KIAA1541 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
KIAA1541 Purity
>90%, as determined by SDS-PAGE under reducing conditions
KIAA1541 Activity
N/A
Tag
KIAA1541 Contains A 6x histidine tag
KIAA1541 Formulation
Liquid
KIAA1541 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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KIAA1541 family
Phosphatase 2A regulatory subunit B family
KIAA1541 Subcellular locations
Cytoplasm.
KIAA1541 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
KIAA1541 Sequence
DDBJ EMBL GenBank
KIAA1541 3D structure
ModBase
KIAA1541 interaction
STRING
KIAA1541 Proteomic
PRIDE
KIAA1541 Proteomic
Ensembl GeneID KEGG UCSC
KIAA1541 Organism specific
CTD MGI
KIAA1541 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
KIAA1541 Gene expression
Bgee ArrayExpress Genevestigator
KIAA1541 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY