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Human Inositol polyphosphate 5-phosphatase K (aa 1-448)

PPS Swiss Prot#

Q9BT40

PPS Protein names

Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Skeletal muscle and kidney-enriched inositol phosphatase)

PPS Gene names

INPP5K (PPS) (SKIP)

Organism

Human

PPS Entry name

INP5K_HUMAN

PPS Codon optimized cDNA(gene) Clone

PPS Cat #

RPT0283

Tag

PPS contains A 6x histidine tag

PPS Formulation

Liquid

PPS Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PPS Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPS Protein

PPS Cat #

PT0283

PPS Source

recombinant

PPS Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PPS Purity

>90%, as determined by SDS-PAGE under reducing conditions

PPS Activity

N/A

Tag

PPS Contains A 6x histidine tag

PPS Formulation

Liquid

PPS Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PPS family

Inositol-1,4,5-trisphosphate 5-phosphatase type II family

PPS Subcellular locations

Endoplasmic reticulum.

PPS FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.

PPS Sequence

DDBJ

EMBL

GenBank

PPS 3D structure

ModBase

PPS interaction

STRING

PPS Proteomic

PRIDE

PPS Proteomic

Ensembl

GeneID

KEGG

UCSC

PPS Organism specific

CTD

MGI

PPS Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PPS Gene expression

Bgee

ArrayExpress

Genevestigator

PPS Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY