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Human Serine threonine-protein phosphatase 4 regulatory 2 (aa 1-417)

SBBI57 Swiss Prot#

Q9NY27

SBBI57 Protein names

Serine/threonine-protein phosphatase 4 regulatory subunit 2

SBBI57 Gene names

PPP4R2 (SBBI57)

Organism

Human

SBBI57 Entry name

PP4R2_HUMAN

SBBI57 Codon optimized cDNA(gene) Clone

SBBI57 Cat #

RPT0265

Tag

SBBI57 contains A 6x histidine tag

SBBI57 Formulation

Liquid

SBBI57 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SBBI57 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SBBI57 Protein

SBBI57 Cat #

PT0265

SBBI57 Source

recombinant

SBBI57 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SBBI57 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SBBI57 Activity

N/A

Tag

SBBI57 Contains A 6x histidine tag

SBBI57 Formulation

Liquid

SBBI57 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SBBI57 family

PPP4R2 family

SBBI57 Subcellular locations

Cytoplasm > cytoskeleton > centrosome.

SBBI57 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

SBBI57 Sequence

DDBJ

EMBL

GenBank

SBBI57 3D structure

ModBase

SBBI57 interaction

STRING

SBBI57 Proteomic

PRIDE

SBBI57 Proteomic

Ensembl

GeneID

KEGG

UCSC

SBBI57 Organism specific

CTD

MGI

SBBI57 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SBBI57 Gene expression

Bgee

ArrayExpress

Genevestigator

SBBI57 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY