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Human Protein phosphatase 1A (aa 1-382)

PPPM1A Swiss Prot#

P35813

PPPM1A Protein names

Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (IA)

PPPM1A Gene names

PPM1A (PPPM1A)

Organism

Human

PPPM1A Entry name

PPM1A_HUMAN

PPPM1A Codon optimized cDNA(gene) Clone

PPPM1A Cat #

RPT0224

Tag

PPPM1A contains A 6x histidine tag

PPPM1A Formulation

Liquid

PPPM1A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PPPM1A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPPM1A Protein

PPPM1A Cat #

PT0224

PPPM1A Source

recombinant

PPPM1A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PPPM1A Purity

>90%, as determined by SDS-PAGE under reducing conditions

PPPM1A Activity

N/A

Tag

PPPM1A Contains A 6x histidine tag

PPPM1A Formulation

Liquid

PPPM1A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PPPM1A family

PP2C family

PPPM1A Subcellular locations

Nucleus.

PPPM1A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.

PPPM1A Sequence

DDBJ

EMBL

GenBank

PPPM1A 3D structure

ModBase

PPPM1A interaction

STRING

PPPM1A Proteomic

PRIDE

PPPM1A Proteomic

Ensembl

GeneID

KEGG

UCSC

PPPM1A Organism specific

CTD

MGI

PPPM1A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PPPM1A Gene expression

Bgee

ArrayExpress

Genevestigator

PPPM1A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY