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| Human Cytoplasmic protein NCK1 (aa 1-377) |
| NCK Swiss Prot# | | P16333 |
| NCK Protein names | | Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) (SH2/SH3 adaptor protein NCK-alpha) |
| NCK Gene names | | NCK1 (NCK) |
| Organism | | Human |
| NCK Entry name | | NCK1_HUMAN |
| NCK Codon optimized cDNA(gene) Clone |
| NCK Cat # | | RPT0219 |
| Tag | | NCK contains A 6x histidine tag |
| NCK Formulation | | Liquid |
| NCK Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| NCK Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant NCK Protein |
| NCK Cat # | | PT0219 |
| NCK Source | | recombinant |
| NCK Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| NCK Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| NCK Activity | | N/A |
| Tag | | NCK Contains A 6x histidine tag |
| NCK Formulation | | Liquid |
| NCK Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant NCK Products | | For pricing and availability Click Here >>> |
| NCK family | | - |
| NCK Subcellular locations | | Cytoplasm. Endoplasmic reticulum. Nucleus. |
| NCK FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. |
| NCK Sequence | | DDBJ | EMBL | GenBank |
| NCK 3D structure | | ModBase |
| NCK interaction | | STRING |
| NCK Proteomic | | PRIDE |
| NCK Proteomic | | Ensembl | GeneID | KEGG | UCSC |
| NCK Organism specific | | CTD | MGI |
| NCK Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| NCK Gene expression | | Bgee | ArrayExpress | Genevestigator |
| NCK Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |