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Human Aprataxin (aa 1-356)

AXA1 Swiss Prot#

Q7Z2E3

AXA1 Protein names

Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)

AXA1 Gene names

APTX (AXA1)

Organism

Human

AXA1 Entry name

APTX_HUMAN

AXA1 Codon optimized cDNA(gene) Clone

AXA1 Cat #

RPT0205

Tag

AXA1 contains A 6x histidine tag

AXA1 Formulation

Liquid

AXA1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

AXA1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant AXA1 Protein

AXA1 Cat #

PT0205

AXA1 Source

recombinant

AXA1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

AXA1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

AXA1 Activity

N/A

Tag

AXA1 Contains A 6x histidine tag

AXA1 Formulation

Liquid

AXA1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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AXA1 family

-

AXA1 Subcellular locations

Nucleus > nucleoplasm. Nucleus > nucleolus.

AXA1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

AXA1 Sequence

DDBJ

EMBL

GenBank

AXA1 3D structure

ModBase

AXA1 interaction

STRING

AXA1 Proteomic

PRIDE

AXA1 Proteomic

Ensembl

GeneID

KEGG

UCSC

AXA1 Organism specific

CTD

MGI

AXA1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

AXA1 Gene expression

Bgee

ArrayExpress

Genevestigator

AXA1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY