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Human Serine threonine-protein phosphatase PP1-alpha (aa 1-330)

PPP1A Swiss Prot#

P62136

PPP1A Protein names

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)

PPP1A Gene names

PPP1CA (PPP1A)

Organism

Human

PPP1A Entry name

PP1A_HUMAN

PPP1A Codon optimized cDNA(gene) Clone

PPP1A Cat #

RPT0184

Tag

PPP1A contains A 6x histidine tag

PPP1A Formulation

Liquid

PPP1A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PPP1A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPP1A Protein

PPP1A Cat #

PT0184

PPP1A Source

recombinant

PPP1A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PPP1A Purity

>90%, as determined by SDS-PAGE under reducing conditions

PPP1A Activity

N/A

Tag

PPP1A Contains A 6x histidine tag

PPP1A Formulation

Liquid

PPP1A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PPP1A family

PPP phosphatase family, PP-1 subfamily

PPP1A Subcellular locations

Cytoplasm. Nucleus. Nucleus > nucleoplasm. Nucleus > nucleolus.

PPP1A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

PPP1A Sequence

DDBJ

EMBL

GenBank

PPP1A 3D structure

ModBase

PPP1A interaction

STRING

PPP1A Proteomic

PRIDE

PPP1A Proteomic

Ensembl

GeneID

KEGG

UCSC

PPP1A Organism specific

CTD

MGI

PPP1A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PPP1A Gene expression

Bgee

ArrayExpress

Genevestigator

PPP1A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY