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Human Serine threonine-protein phosphatase 6 catalytic (aa 1-305)

PPP6 Swiss Prot#

O00743

PPP6 Protein names

Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16)

PPP6 Gene names

PPP6C (PPP6)

Organism

Human

PPP6 Entry name

PPP6_HUMAN

PPP6 Codon optimized cDNA(gene) Clone

PPP6 Cat #

RPT0158

Tag

PPP6 contains A 6x histidine tag

PPP6 Formulation

Liquid

PPP6 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PPP6 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPP6 Protein

PPP6 Cat #

PT0158

PPP6 Source

recombinant

PPP6 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PPP6 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PPP6 Activity

N/A

Tag

PPP6 Contains A 6x histidine tag

PPP6 Formulation

Liquid

PPP6 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PPP6 family

PPP phosphatase family, PP-6 (PP-V) subfamily

PPP6 Subcellular locations

Cytoplasm.

PPP6 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalytic subunit of protein phospatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

PPP6 Sequence

DDBJ

EMBL

GenBank

PPP6 3D structure

ModBase

PPP6 interaction

STRING

PPP6 Proteomic

PRIDE

PPP6 Proteomic

Ensembl

GeneID

KEGG

UCSC

PPP6 Organism specific

CTD

MGI

PPP6 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PPP6 Gene expression

Bgee

ArrayExpress

Genevestigator

PPP6 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY