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Human Protein phosphatase 1 regulatory subunit 3B (aa 1-285)

PPP1R4 Swiss Prot#

Q86XI6

PPP1R4 Protein names

Protein phosphatase 1 regulatory subunit 3B (Protein phosphatase 1 regulatory subunit 4) (R4) (Protein phosphatase 1 subunit GL) (Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL)

PPP1R4 Gene names

PPP1R3B (PPP1R4)

Organism

Human

PPP1R4 Entry name

PPR3B_HUMAN

PPP1R4 Codon optimized cDNA(gene) Clone

PPP1R4 Cat #

RPT0147

Tag

PPP1R4 contains A 6x histidine tag

PPP1R4 Formulation

Liquid

PPP1R4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PPP1R4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPP1R4 Protein

PPP1R4 Cat #

PT0147

PPP1R4 Source

recombinant

PPP1R4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PPP1R4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PPP1R4 Activity

N/A

Tag

PPP1R4 Contains A 6x histidine tag

PPP1R4 Formulation

Liquid

PPP1R4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PPP1R4 family

-

PPP1R4 Subcellular locations

-

PPP1R4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).

PPP1R4 Sequence

DDBJ

EMBL

GenBank

PPP1R4 3D structure

ModBase

PPP1R4 interaction

STRING

PPP1R4 Proteomic

PRIDE

PPP1R4 Proteomic

Ensembl

GeneID

KEGG

UCSC

PPP1R4 Organism specific

CTD

MGI

PPP1R4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PPP1R4 Gene expression

Bgee

ArrayExpress

Genevestigator

PPP1R4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY