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Human Myelin protein zero-like protein 1 (aa 36-269)

PZR Swiss Prot#

O95297

PZR Protein names

Myelin protein zero-like protein 1 (Protein zero-related)

PZR Gene names

MPZL1 (PZR) (UNQ849/PRO1787)

Organism

Human

PZR Entry name

MPZL1_HUMAN

PZR Codon optimized cDNA(gene) Clone

PZR Cat #

RPT0103

Tag

PZR contains A 6x histidine tag

PZR Formulation

Liquid

PZR Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PZR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PZR Protein

PZR Cat #

PT0103

PZR Source

recombinant

PZR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PZR Purity

>90%, as determined by SDS-PAGE under reducing conditions

PZR Activity

N/A

Tag

PZR Contains A 6x histidine tag

PZR Formulation

Liquid

PZR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PZR family

Myelin P0 protein family

PZR Subcellular locations

Membrane; Single-pass type I membrane protein.

PZR FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

PZR Sequence

DDBJ

EMBL

GenBank

PZR 3D structure

ModBase

PZR interaction

STRING

PZR Proteomic

PRIDE

PZR Proteomic

Ensembl

GeneID

KEGG

UCSC

PZR Organism specific

CTD

MGI

PZR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PZR Gene expression

Bgee

ArrayExpress

Genevestigator

PZR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY