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Human Peptidyl-prolyl cis-trans isomerase FKBP1A (aa 1-108)

FKBP1 Swiss Prot#

P62942

FKBP1 Protein names

Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (EC 5.2.1.8) (FK506-binding protein 1A) (FKBP-1A) (Rotamase) (Immunophilin FKBP12) (12 kDa FKBP) (FKBP-12)

FKBP1 Gene names

FKBP1A (FKBP1) (FKBP12)

Organism

Human

FKBP1 Entry name

FKB1A_HUMAN

FKBP1 Codon optimized cDNA(gene) Clone

FKBP1 Cat #

RPT0010

Tag

FKBP1 contains A 6x histidine tag

FKBP1 Formulation

Liquid

FKBP1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FKBP1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FKBP1 Protein

FKBP1 Cat #

PT0010

FKBP1 Source

recombinant

FKBP1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FKBP1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

FKBP1 Activity

N/A

Tag

FKBP1 Contains A 6x histidine tag

FKBP1 Formulation

Liquid

FKBP1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FKBP1 family

FKBP-type PPIase family, FKBP1 subfamily

FKBP1 Subcellular locations

Cytoplasm.

FKBP1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

FKBP1 Sequence

DDBJ

EMBL

GenBank

FKBP1 3D structure

ModBase

FKBP1 interaction

STRING

FKBP1 Proteomic

PRIDE

FKBP1 Proteomic

Ensembl

GeneID

KEGG

UCSC

FKBP1 Organism specific

CTD

MGI

FKBP1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FKBP1 Gene expression

Bgee

ArrayExpress

Genevestigator

FKBP1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY