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Mouse Sphingosine kinase 1 (aa 28-382)

Sphk1 Swiss Prot#

Q8CI15

Sphk1 Protein names

Sphingosine kinase 1 (SPK 1) (SK 1) (EC 2.7.1.91)

Sphk1 Gene names

Sphk1

Organism

Mouse

Sphk1 Entry name

SPHK1_MOUSE

Sphk1 Codon optimized cDNA(gene) Clone

Sphk1 Cat #

RPX2849

Tag

Sphk1 contains A 6x histidine tag

Sphk1 Formulation

Liquid

Sphk1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Sphk1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Sphk1 Protein

Sphk1 Cat #

PX2849

Sphk1 Source

recombinant

Sphk1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Sphk1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Sphk1 Activity

N/A

Tag

Sphk1 Contains A 6x histidine tag

Sphk1 Formulation

Liquid

Sphk1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Sphk1 family

-

Sphk1 Subcellular locations

Cytoplasm. Nucleus.

Sphk1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol (By similarity).

Sphk1 Sequence

DDBJ

EMBL

GenBank

Sphk1 3D structure

ModBase

Sphk1 interaction

STRING

Sphk1 Proteomic

PRIDE

Sphk1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Sphk1 Organism specific

CTD

MGI

Sphk1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Sphk1 Gene expression

Bgee

ArrayExpress

Genevestigator

Sphk1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY