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Mouse Kallikrein-14 (aa 18-250)

Gk14 Swiss Prot#

Q8CGR5

Gk14 Protein names

Kallikrein-14 (EC 3.4.21.-) (Kallikrein related-peptidase 14) (Glandular kallikrein KLK14) (mGK14)

Gk14 Gene names

Klk14 Gk14

Organism

Mouse

Gk14 Entry name

KLK14_MOUSE

Gk14 Codon optimized cDNA(gene) Clone

Gk14 Cat #

RPX1454

Tag

Gk14 contains A 6x histidine tag

Gk14 Formulation

Liquid

Gk14 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Gk14 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Gk14 Protein

Gk14 Cat #

PX1454

Gk14 Source

recombinant

Gk14 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Gk14 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Gk14 Activity

N/A

Tag

Gk14 Contains A 6x histidine tag

Gk14 Formulation

Liquid

Gk14 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Gk14 family

Peptidase S1 family, Kallikrein subfamily

Gk14 Subcellular locations

Secreted > extracellular space.

Gk14 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis (By similarity).

Gk14 Sequence

DDBJ

EMBL

GenBank

Gk14 3D structure

ModBase

Gk14 interaction

STRING

Gk14 Proteomic

PRIDE

Gk14 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Gk14 Organism specific

CTD

MGI

Gk14 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Gk14 Gene expression

Bgee

ArrayExpress

Genevestigator

Gk14 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY