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Mouse Inward rectifier potassium channel 4 (aa 1-445)

Irk3 Swiss Prot#

P52189

Irk3 Protein names

Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK-3)

Irk3 Gene names

Kcnj4 Irk3

Organism

Mouse

Irk3 Entry name

IRK4_MOUSE

Irk3 Codon optimized cDNA(gene) Clone

Irk3 Cat #

RPX1444

Tag

Irk3 contains A 6x histidine tag

Irk3 Formulation

Liquid

Irk3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Irk3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Irk3 Protein

Irk3 Cat #

PX1444

Irk3 Source

recombinant

Irk3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Irk3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Irk3 Activity

N/A

Tag

Irk3 Contains A 6x histidine tag

Irk3 Formulation

Liquid

Irk3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Irk3 family

Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ4 subfamily

Irk3 Subcellular locations

Membrane; Multi-pass membrane protein.

Irk3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).

Irk3 Sequence

DDBJ

EMBL

GenBank

Irk3 3D structure

ModBase

Irk3 interaction

STRING

Irk3 Proteomic

PRIDE

Irk3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Irk3 Organism specific

CTD

MGI

Irk3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Irk3 Gene expression

Bgee

ArrayExpress

Genevestigator

Irk3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY