All rights
reserved
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mouse Dynein light chain Tctex-type 1 (aa 1-113) |
| Tctel1 Swiss Prot# | | P51807 |
| Tctel1 Protein names | | Dynein light chain Tctex-type 1 (T-complex testis-specific protein 1) (TCTEX-1) (Activator of G-protein signaling 2) (AGS2) |
| Tctel1 Gene names | | Dynlt1 Tctel1 Tctex-1 Tctex1 |
| Organism | | Mouse |
| Tctel1 Entry name | | DYLT1_MOUSE |
| Tctel1 Codon optimized cDNA(gene) Clone |
| Tctel1 Cat # | | RPX1386 |
| Tag | | Tctel1 contains A 6x histidine tag |
| Tctel1 Formulation | | Liquid |
| Tctel1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Tctel1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Tctel1 Protein |
| Tctel1 Cat # | | PX1386 |
| Tctel1 Source | | recombinant |
| Tctel1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Tctel1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Tctel1 Activity | | N/A |
| Tag | | Tctel1 Contains A 6x histidine tag |
| Tctel1 Formulation | | Liquid |
| Tctel1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Tctel1 Products | | For pricing and availability Click Here >>> |
| Tctel1 family | | Dynein light chain Tctex-type family |
| Tctel1 Subcellular locations | | Golgi apparatus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. |
| Tctel1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site (By similarity). May also be a accessory component of axonemal dynein. Plays an important role in male germ cell development and function. Candidate for involvement in male sterility.; FUNCTION: Plays a role in neuronal morhpogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation. |
| Tctel1 Sequence | | DDBJ | EMBL | GenBank |
| Tctel1 3D structure | | ModBase |
| Tctel1 interaction | | STRING |
| Tctel1 Proteomic | | PRIDE |
| Tctel1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Tctel1 Organism specific | | CTD | MGI |
| Tctel1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Tctel1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Tctel1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
