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Mouse Drebrin-like protein (aa 1-436)

Abp1 Swiss Prot#

Q62418

Abp1 Protein names

Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1)

Abp1 Gene names

Dbnl Abp1 Sh3p7

Organism

Mouse

Abp1 Entry name

DBNL_MOUSE

Abp1 Codon optimized cDNA(gene) Clone

Abp1 Cat #

RPX1374

Tag

Abp1 contains A 6x histidine tag

Abp1 Formulation

Liquid

Abp1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Abp1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Abp1 Protein

Abp1 Cat #

PX1374

Abp1 Source

recombinant

Abp1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Abp1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Abp1 Activity

N/A

Tag

Abp1 Contains A 6x histidine tag

Abp1 Formulation

Liquid

Abp1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Abp1 family

ABP1 family

Abp1 Subcellular locations

Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cell projection > ruffle.

Abp1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.

Abp1 Sequence

DDBJ

EMBL

GenBank

Abp1 3D structure

ModBase

Abp1 interaction

STRING

Abp1 Proteomic

PRIDE

Abp1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Abp1 Organism specific

CTD

MGI

Abp1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Abp1 Gene expression

Bgee

ArrayExpress

Genevestigator

Abp1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY