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Mouse Histamine H1 receptor (aa 43-488)

Bphs Swiss Prot#

P70174

Bphs Protein names

Histamine H1 receptor (HH1R) (H1R)

Bphs Gene names

Hrh1 Bphs

Organism

Mouse

Bphs Entry name

HRH1_MOUSE

Bphs Codon optimized cDNA(gene) Clone

Bphs Cat #

RPX1361

Tag

Bphs contains A 6x histidine tag

Bphs Formulation

Liquid

Bphs Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Bphs Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Bphs Protein

Bphs Cat #

PX1361

Bphs Source

recombinant

Bphs Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Bphs Purity

>90%, as determined by SDS-PAGE under reducing conditions

Bphs Activity

N/A

Tag

Bphs Contains A 6x histidine tag

Bphs Formulation

Liquid

Bphs Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Bphs family

G-protein coupled receptor 1 family

Bphs Subcellular locations

Cell membrane; Multi-pass membrane protein.

Bphs FUNCTION According to UniProtKB Swiss Prot

FUNCTION: In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. Involved in circadian rhythm of locomotor activity and exploratory behavior. Also involved in responsiveness to pertussis toxin through its control of susceptibility to histamine hypersensitivity and enhancement of antigen-specific delayed-type hypersensitivity responses.

Bphs Sequence

DDBJ

EMBL

GenBank

Bphs 3D structure

ModBase

Bphs interaction

STRING

Bphs Proteomic

PRIDE

Bphs Genome annotation

Ensembl

GeneID

KEGG

UCSC

Bphs Organism specific

CTD

MGI

Bphs Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Bphs Gene expression

Bgee

ArrayExpress

Genevestigator

Bphs Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY