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Mouse KiSS-1 receptor (aa 1-396)

Gpr54 Swiss Prot#

Q91V45

Gpr54 Protein names

KiSS-1 receptor (KiSS-1R) (Kisspeptins receptor) (Metastin receptor) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (mOT7T175)

Gpr54 Gene names

Kiss1r Gpr54

Organism

Mouse

Gpr54 Entry name

KISSR_MOUSE

Gpr54 Codon optimized cDNA(gene) Clone

Gpr54 Cat #

RPX1281

Tag

Gpr54 contains A 6x histidine tag

Gpr54 Formulation

Liquid

Gpr54 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Gpr54 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Gpr54 Protein

Gpr54 Cat #

PX1281

Gpr54 Source

recombinant

Gpr54 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Gpr54 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Gpr54 Activity

N/A

Tag

Gpr54 Contains A 6x histidine tag

Gpr54 Formulation

Liquid

Gpr54 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Gpr54 family

G-protein coupled receptor 1 family

Gpr54 Subcellular locations

Cell membrane; Multi-pass membrane protein.

Gpr54 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for metastin (kisspeptin-52 or kp-52), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Gpr54 Sequence

DDBJ

EMBL

GenBank

Gpr54 3D structure

ModBase

Gpr54 interaction

STRING

Gpr54 Proteomic

PRIDE

Gpr54 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Gpr54 Organism specific

CTD

MGI

Gpr54 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Gpr54 Gene expression

Bgee

ArrayExpress

Genevestigator

Gpr54 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY