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Mouse C-X-C chemokine receptor type 4 (aa 1-359)

Cmkar4 Swiss Prot#

P70658

Cmkar4 Protein names

C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Pre-B-cell-derived chemokine receptor) (PB-CKR) (CD antigen CD184)

Cmkar4 Gene names

Cxcr4 Cmkar4 Lestr Sdf1r

Organism

Mouse

Cmkar4 Entry name

CXCR4_MOUSE

Cmkar4 Codon optimized cDNA(gene) Clone

Cmkar4 Cat #

RPX1200

Tag

Cmkar4 contains A 6x histidine tag

Cmkar4 Formulation

Liquid

Cmkar4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cmkar4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cmkar4 Protein

Cmkar4 Cat #

PX1200

Cmkar4 Source

recombinant

Cmkar4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cmkar4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cmkar4 Activity

N/A

Tag

Cmkar4 Contains A 6x histidine tag

Cmkar4 Formulation

Liquid

Cmkar4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cmkar4 family

G-protein coupled receptor 1 family

Cmkar4 Subcellular locations

Cell membrane; Multi-pass membrane protein.

Cmkar4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Cmkar4 Sequence

DDBJ

EMBL

GenBank

Cmkar4 3D structure

ModBase

Cmkar4 interaction

STRING

Cmkar4 Proteomic

PRIDE

Cmkar4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cmkar4 Organism specific

CTD

MGI

Cmkar4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cmkar4 Gene expression

Bgee

ArrayExpress

Genevestigator

Cmkar4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY