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Human Sphingosine kinase 1 (aa 32-384)

SPHK Swiss Prot#

Q9NYA1

SPHK Protein names

Sphingosine kinase 1 (SPK 1) (SK 1) (EC 2.7.1.91)

SPHK Gene names

SPHK1 SPHK SPK

Organism

Human

SPHK Entry name

SPHK1_HUMAN

SPHK Codon optimized cDNA(gene) Clone

SPHK Cat #

RPX0958

Tag

SPHK contains A 6x histidine tag

SPHK Formulation

Liquid

SPHK Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SPHK Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SPHK Protein

SPHK Cat #

PX0958

SPHK Source

recombinant

SPHK Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SPHK Purity

>90%, as determined by SDS-PAGE under reducing conditions

SPHK Activity

N/A

Tag

SPHK Contains A 6x histidine tag

SPHK Formulation

Liquid

SPHK Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SPHK family

-

SPHK Subcellular locations

Cytoplasm. Nucleus.

SPHK FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

SPHK Sequence

DDBJ

EMBL

GenBank

SPHK 3D structure

ModBase

SPHK interaction

STRING

SPHK Proteomic

PRIDE

SPHK Genome annotation

Ensembl

GeneID

KEGG

UCSC

SPHK Organism specific

CTD

MGI

SPHK Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SPHK Gene expression

Bgee

ArrayExpress

Genevestigator

SPHK Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY