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Human Orexin (aa 32-131)

OX Swiss Prot#

O43612

OX Protein names

Orexin (Hypocretin) (Hcrt) [Cleaved into: Orexin-A (Hypocretin-1) (Hcrt1); Orexin-B (Hypocretin-2) (Hcrt2)]

OX Gene names

HCRT OX PPORX PPOX

Organism

Human

OX Entry name

OREX_HUMAN

OX Codon optimized cDNA(gene) Clone

OX Cat #

RPX0794

Tag

OX contains A 6x histidine tag

OX Formulation

Liquid

OX Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

OX Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant OX Protein

OX Cat #

PX0794

OX Source

recombinant

OX Applications

Western Blot, SDS-Page or may be used for other applications determined by user

OX Purity

>90%, as determined by SDS-PAGE under reducing conditions

OX Activity

N/A

Tag

OX Contains A 6x histidine tag

OX Formulation

Liquid

OX Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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OX family

Orexin family

OX Subcellular locations

Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction > synapse.

OX FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

OX Sequence

DDBJ

EMBL

GenBank

OX 3D structure

ModBase

OX interaction

STRING

OX Proteomic

PRIDE

OX Genome annotation

Ensembl

GeneID

KEGG

UCSC

OX Organism specific

CTD

MGI

OX Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

OX Gene expression

Bgee

ArrayExpress

Genevestigator

OX Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY