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Human Azurocidin (aa 26-251)
AZU1 Swiss Prot#
P20160
AZU1 Protein names
Azurocidin (Cationic antimicrobial protein CAP37) (Heparin-binding protein) (HBP)
AZU1 Gene names
AZU1
Organism
Human
AZU1 Entry name
CAP7_HUMAN
AZU1 Codon optimized cDNA(gene) Clone
AZU1 Cat #
RPX0734
Tag
AZU1 contains A 6x histidine tag
AZU1 Formulation
Liquid
AZU1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
AZU1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant AZU1 Protein
AZU1 Cat #
PX0734
AZU1 Source
recombinant
AZU1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
AZU1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
AZU1 Activity
N/A
Tag
AZU1 Contains A 6x histidine tag
AZU1 Formulation
Liquid
AZU1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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AZU1 family
Peptidase S1 family, Elastase subfamily
AZU1 Subcellular locations
Cytoplasmic granule.
AZU1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
AZU1 Sequence
DDBJ EMBL GenBank
AZU1 3D structure
ModBase
AZU1 interaction
STRING
AZU1 Proteomic
PRIDE
AZU1 Genome annotation
Ensembl GeneID KEGG UCSC
AZU1 Organism specific
CTD MGI
AZU1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
AZU1 Gene expression
Bgee ArrayExpress Genevestigator
AZU1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY